CCMI - Presentation

Integrative Genomic Analysis with GenePattern

Hosted by Michael Reich, Assistant Director of Bioinformatics, UC San Diego 

Organized by the Cancer Cell Map Initiative (CCMI) 

GenePattern, www.genepattern.org, enables researchers at all levels of computational expertise to use hundreds of tools for the analysis of gene expression, sequence variation, proteomics, and more, through an intuitive interface that requires no coding. 

GenePattern makes reproducible research easy: analyses can be rerun at any time with the same inputs; every version of each tool is tracked, so that a result can be reproduced even if the code that produced it changes in the future; and researchers can chain analyses together to encapsulate and share their research as reproducible workflows. 

A new GenePattern Notebook environment, www.genepattern-notebook.org, based on the popular Jupyter Notebook system, further allows users to interleave text, graphics, and analyses in unified "research narratives" that can be shared and published. 

In this hands-on workshop, participants will learn how to: 

  • Identify analyses relevant to their scientific objectives 
  • Analyze and visualize gene expression (including RNA-seq) and other genomic data
  • Ensure that their analyses are reproducible
  • Create and publish research narratives that serve as a live, executable, shareable representation of a study


Schedule

8:45AM Doors Open  

9:00 AM GenePattern Overview

9:10 AM Introduction to GenePattern Notebook

9:50 AM Data Preparation

10:20 AM Jupyter Basics

10:35 AM Using Python code and dataframes

10:45 AM Break

11:00 AM Differential Gene Expression Analysis

11:45 AM Gene Set Enrichment Analysis (GSEA)

12:15 PM Lunch break

1:00 PM Clustering

1:45 PM Dimension Reduction

2:15 PM Classification and Prediction

2:45 PM Break

3:00 PM GenePattern Notebook and Python

3:30 PM Integrative Genomics Viewer (IGV)

3:45 PM Class Project

4:30 PM Other GenePattern Features/Closing

** Coffee and light lunch provided **

No Show Policy 

While we do not charge a fee to attend this event, these programs would not be sustainable and available to all wanting to attend, unless all registrants abide by the 48 hour cancellation notice policy. A no-show will also limit your ability to book our events in the future. Thank you in advance for your cooperation.

Directions

A map of Pharmaceutical Sciences Building (PSB) and the nearby parking lots can be viewed here. If using the UC San Diego Shuttle, exit at Gilman Drive and Meyers Lane, then walk south towards School of Medicine. The closest parking lots include the Osler Parking Structure, P602, P603 and the Gilman Parking structure. Hourly rates are posted at meters; cards are accepted. Additionally, Valet Parking is available in lot P610 on Osler Lane.  

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