ANNOUNCEMENT: We are excited to announce that the 2018 Cell Mapping Symposium was live-streamed and recorded videos are now available on YouTube. Click HERE to view a playlist of all videos. Additionally, each speaker's individual video recording are linked below.  

The Cell Mapping Symposium will address cell mapping as it relates to cancer, psychiatric disorders, infectious diseases and technology development. A major motivation of this symposium is the realization that although much insight has been gained from large genome sequencing projects, effort now needs to be placed on extracting mechanistic insight from these data. These efforts include using proteomic, biochemical, genetic and structural biology approaches to generate cellular maps that can be used to interpret this genomic data from a variety of different disease areas.

This exciting, full-day symposium will feature talks from a variety of distinguished speakers and will be held at the Sanford Consortium for Regenerative Medicine in La Jolla, CA (MAP). The symposium begins at 9:00 AM on Monday, October 29, 2018  and will conclude with an evening reception at 6:00 PM. Refreshments and lunch are provided. Free to attend, but registration is required. Register Here (SOLD OUT).  

About Cell Mapping 

The ability of a cell to respond to its environment depends on the actions of the proteins encoded by the DNA in the genome. However, most proteins don’t work alone. They work with other proteins in teams called complexes. The principles of “cell mapping” are to figure out which proteins work together in complexes. Mapping can be done in different disease states or in the presence of different chemical drugs. To accomplish these goals, researchers augment these cell maps with genetic maps to derive quantitative insights into how biological functions of cells can be restored. 

One of the main objectives of this symposium is to discuss technological advances in extracting mechanistic insight from these large genome sequencing projects. These efforts include using proteomic, biochemical, genetic, and structural biology approaches to generate cellular maps that can be used to interpret this genomic data from a variety of different disease areas.  

Schedule (*subject to change)

• 8:30 AM Registration / Coffee
• 9:00 AM Opening remarks by Trey Ideker and Nevan Krogan (YouTube)

Session 1: Mapping Technology

• 9:10 AM Emma Lundberg, KTH Royal Institute of Technology. "Spatiotemporal Proteome Organization of the Human Cell" (YouTube)
• 9:30 AM Nozomu Yachie, University of Tokyo. "Chasing molecular and cellular dynamics using DNA barcodes" (No Video)
• 9:50 AM Wade Harper, Harvard Medical School. "Quantifying Interactomes and Signalling Networks" (YouTube)
• 10:10 AM Michael Bassik, Stanford University. "Development of new CRISPR/Cas9-based tools to study drug interactions through knockout and directed evolution" (YouTube)
• 10:30 AM Coffee break

Session 2: Psychiatric Mapping

• 10:50 AM Abraham Palmer, UC San Diego. "Ratification of network research (aka using rats as a model system)" (YouTube)
• 11:10 AM Kristin Baldwin, Scripps Research Institute. "Driving and defining neuronal transcriptional diversity using reprogramming" (YouTube)
• 11:30 AM Alysson Muotri, UC San Diego. "Brain organoids as a model to understand the contribution of cell populations to networks oscillations" ( YouTube)
• 11:50 PM Lunch

Session 3: Cancer Mapping

• 1:00 PM Barry Honig, Columbia University. “Structure-based protein-protein interaction networks and cancer-related applications” (YouTube)
• 1:20 PM Kasper Lage, Harvard Medical School. "Expanding discovery from cancer genomes by integrating network analyses with massively parallel in vivo tumorigenesis assays." (YouTube)
• 1:40 PM Sidi Chen, Yale University. "Towards Mapping Functional Cancer Genome Atlas" (YouTube)
• 2:00 PM Hannah Carter, UC San Diego. "Identifying mutation-specific cancer pathways using structurally resolved interactomes" (YouTube)
• 2:20 PM Ben Raphael, Princeton University. "Networks of non-coding mutations in cancer" (YouTube)
  
• 2:40 PM Coffee break
• 3:00 PM Inna Kuperstein, Curie Institute. "Atlas of Cancer Signaling Network: a multi-scale resource of maps to study disease mechanisms" (YouTube)
• 3:20 PM Rodney Rothstein, Columbia University. "Using yeast to study gene overexpression, an underappreciated perturbation in cancer cells" (YouTube)

Session 4: Infectious Disease Mapping

• 3:40 PM Jan Carette, Stanford University. "Genetic Dissection of Virus-Host Arms Races" (YouTube)
• 4:00 PM Melanie Ott, Gladstone Institutes. "Using Organoid Technology to Study Liver Infections and Immunity" (No Video)
• 4:20 PM Shaeri Mukherjee, UC San Francisco. "Lessons learned from intracellular bacteria: How to re-wire and remodel the host cell" (YouTube)
• 4:40 PM Closing remarks by Trey Ideker and Nevan Krogan (YouTube)
• 5:00 PM Reception 

Parking
Free parking at the Sanford Consortium's east lot will be available on a first-come, first-serve basis. Hourly parking is also available for purchase at the pay station. Additional parking can be found near the Torrey Pines Gliderport, which is within walking distance. The UCSD Shuttle Route has drop off locations within walking distance to the Sanford Consortium. 

No Show Policy 
If you are unable to attend for any reason, please cancel your registration or email (hello@ccmi.org) at least 48 hours prior to the event. A no-show can limit your ability to book our events in the future. Thank you in advance for your cooperation. 

Contact Us  
Cancer Cell Map Initiative 
hello@ccmi.org

#CellMaps2018